Kinase Inhibitors

TC ASK 10 View larger

TC ASK 10

AT13099

CAS 1005775-56-3

More details

Molarity Calculation Cart®

HOW TO ORDER

$44.00

$44.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $19.80 Total: $1,980.00
150 $22.88 Total: $1,144.00
125 $26.84 Total: $671.00
110 $31.68 Total: $316.80
15 $37.40 Total: $187.00

Data sheet

Molecular FormulaC21H23Cl2N5O
Molecular Weight432.35
CAS Numbers1005775-56-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.Cl.CC(C)(C)c1ccc(cc1)C(=O)Nc1cn2cc(ccc2n1)-n1ccnc1
ReferencesTerao Y, et al. Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors. Bioorg Med Chem Lett. 2012 Dec 15;22[24] 7326-9.

More info

TC ASK 10 is a potent, selective and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1,IC50 = 14 nM). The IC50 value for ASK2 is 0.51 ?M.