Kinase Inhibitors

4E2RCat View larger

4E2RCat

AT14044

CAS 432499-63-3

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$82.00

$82.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $36.90 Total: $3,690.00
150 $42.64 Total: $2,132.00
125 $50.02 Total: $1,250.50
110 $59.04 Total: $590.40
15 $69.70 Total: $348.50

Data sheet

Molecular FormulaC22H14ClNO4S2
Molecular Weight455.93
CAS Numbers432499-63-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC(=O)c1cc(ccc1Cl)-c1ccc(C=C2SC(=S)N(Cc3ccccc3)C2=O)o1
ReferencesCencic R, et al. Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication. J Virol. 2011 Jul;85[13] 6381-9.

More info

4E2RCat is an inhibitor of eIF4E-eIF4G interaction (IC50 = 13.5 ?M) and effectively blocks coronavirus replication, as evidenced by reduced viral protein expression and decreased production of infectious virus.