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Kinase Inhibitors

CCT020312 View larger

CCT020312

AT14902

CAS 324759-76-4

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$54.00

$54.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $45.90 Total: $229.50
110 $38.88 Total: $388.80
125 $32.94 Total: $823.50
150 $28.08 Total: $1,404.00
1100 $24.30 Total: $2,430.00

Data sheet

Molecular FormulaC31H30Br2N4O2
Molecular Weight650.4
CAS Numbers324759-76-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCCN(CC)CCC(=O)N1N=C(CC1c1ccc(Br)cc1)c1c(-c2ccccc2)c2cc(Br)ccc2[nH]c1=O
ReferencesStockwell SR, et al.Mechanism-based screen for G1S checkpoint activators identifies a selective activator of EIF2AK3PERK signalling. PLoS One. 2012;7[1] e28568.

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CCT020312 is a selective activator of EIF2AK3 and PERK. CCT020312 durably inhibits cell proliferation and elicits the phosphorylation of EIF2A.