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View larger CDK2-IN-4
AT14916
CAS 2079895-42-2
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $56.95 | Total: $284.75 |
| 1 | 10 | $48.24 | Total: $482.40 |
| 1 | 25 | $40.87 | Total: $1,021.75 |
| 1 | 50 | $34.84 | Total: $1,742.00 |
| 1 | 100 | $30.15 | Total: $3,015.00 |
Data sheet
| Molecular Formula | C23H18N6O2S |
| Molecular Weight | 442.49 |
| CAS Numbers | 2079895-42-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NS(=O)(=O)c1ccc(Nc2nc(-c3cccc(c3)-c3ccccc3)c3[nH]cnc3n2)cc1 |
| References | Coxon CR, et al. Cyclin-Dependent Kinase [CDK] Inhibitors Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines. J Med Chem. 2017 Mar 9;60[5] 1746-1767. |
More info
CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2cyclin A. It shows 2,000-fold selectivity over CDK1cyclin B with IC50 of 86 uM.