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Kinase Inhibitors
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View larger GSK3145095
AT15437
CAS 1622849-43-7
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $69.70 | Total: $348.50 |
| 1 | 10 | $59.04 | Total: $590.40 |
| 1 | 25 | $50.02 | Total: $1,250.50 |
| 1 | 50 | $42.64 | Total: $2,132.00 |
| 1 | 100 | $36.90 | Total: $3,690.00 |
Data sheet
| Molecular Formula | C20H17F2N5O2 |
| Molecular Weight | 397.38 |
| CAS Numbers | 1622849-43-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Fc1cc(F)c2NC(=O)[C@H](CCc2c1)NC(=O)c1n[nH]c(Cc2ccccc2)n1 |
| References | Harris PA, ET AL. Identification of a RIP1 Kinase Inhibitor Clinical Candidate [GSK3145095] for the Treatment of Pancreatic Cancer. ACS Med Chem Lett. 2019 May 9;10[6] 857-862. |
More info
GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential immunomodulatory activities and antineoplastic.