Kinase Inhibitors

RO9021 View larger

RO9021

AT16776

CAS 1446790-62-0

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$67.00

$67.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $30.15 Total: $3,015.00
150 $34.84 Total: $1,742.00
125 $40.87 Total: $1,021.75
110 $48.24 Total: $482.40
15 $56.95 Total: $284.75

Data sheet

Molecular FormulaC18H25N7O
Molecular Weight355.44
CAS Numbers1446790-62-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1ccc(Nc2cc(N[C@@H]3CCCC[C@@H]3N)nnc2C(N)=O)nc1C
ReferencesLiao C, et al. Selective inhibition of spleen tyrosine kinase [SYK] with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses implications for SYK inhibitors in autoimmune disease therapy.

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RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor [average IC50: 5.6 nM].