Kinase Inhibitors

FRAX486 View larger

FRAX486

AOB6119

CAS No:1232030-35-1

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$21.00

$21.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $9.45 Total: $945.00
150 $10.92 Total: $546.00
125 $12.81 Total: $320.25
110 $15.12 Total: $151.20
15 $17.85 Total: $89.25

Data sheet

Molecular Formula(C25H23Cl2FN6O)2 H2O
Molecular Weight522.4
CAS Numbers1232030-35-1
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity 99% (HPLC)

More info

An orally bioavailable and Blood-Brain Barrier (BBB) penetrable small molecule PAK (p21-activated kinase) inhibitor

References:

1.B. M. Dolan, et al, Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486, PNAS, 2013, No 14, Vol 110 pp5671-5676