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View larger ER? degrader-2
AT39727
CAS 2235396-63-9
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $190.40 | Total: $952.00 |
| 1 | 10 | $161.28 | Total: $1,612.80 |
| 1 | 25 | $136.64 | Total: $3,416.00 |
| 1 | 50 | $116.48 | Total: $5,824.00 |
| 1 | 100 | $100.80 | Total: $10,080.00 |
Data sheet
| Molecular Formula | C29H27F3N2O2 |
| Molecular Weight | 492.53 |
| CAS Numbers | 2235396-63-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [H][C@@]1(N(CC(C)(C)F)[C@H](C)Cc2c1[nH]c1ccccc21)c1c(F)cc(cc1F)-c1ccc(cc1)C(O)=O |
| References | Xiaomeng Zhang, et al. Dynamics-Based Discovery of Novel, Potent Benzoic Acid Derivatives as Orally Bioavailable Selective Estrogen Receptor Degraders for ER?+ Breast Cancer. J Med Chem |
More info
ER? degrader-2 is a selective and potent estrogen receptor (SERD) degrader with anticancer activity, exhibiting an EC50 value of 0.3 nM for ER? degradation. It can be used for the prevention and treatment of HER-positive breast cancer.