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Kinase Inhibitors

CDK46-IN-6 View larger

CDK46-IN-6

AT39957

CAS 2380321-51-5

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$98.00

$98.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $83.30 Total: $416.50
110 $70.56 Total: $705.60
125 $59.78 Total: $1,494.50
150 $50.96 Total: $2,548.00
1100 $44.10 Total: $4,410.00

Data sheet

Molecular FormulaC22H27ClFN5O3
Molecular Weight463.93
CAS Numbers2380321-51-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)n1c(nc2c(F)cc(cc12)-c1nc(N[C@@H]2CCOC[C@H]2O)ncc1Cl)C(C)(C)O
ReferencesPing Chen, et al. 2-amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors. WO2019207463A1.

More info

CDK46-IN-6 is a potent CDK4CDK6 inhibitor with Ki of 0.6 nM and 13.9 nM for CDK4Cyclin D1 and CDK6Cyclin D3, respectively.