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View larger CHMFL-BMX-078
AT4268
CAS 1808288-51-8
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $57.80 | Total: $289.00 |
| 1 | 10 | $48.96 | Total: $489.60 |
| 1 | 25 | $41.48 | Total: $1,037.00 |
| 1 | 50 | $35.36 | Total: $1,768.00 |
| 1 | 100 | $30.60 | Total: $3,060.00 |
Data sheet
| Molecular Formula | C33H35N7O6 |
| Molecular Weight | 625.67 |
| CAS Numbers | 1808288-51-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CNc1nc(Nc2ccc(C)c(NC(=O)C=C)c2)ncc1C(=O)Nc1cc(NC(=O)c2cc(OC)c(OC)c(OC)c2)ccc1C |
| References | Liang X, et al. Discovery of 2-[[3-Acrylamido-4-methylphenyl]amino]-N-[2-methyl-5-[3,4,5-trimethoxybenzamido]phenyl]-4-[methylamino]pyrimidine-5-carboxamide [CHMFL-BMX-078] as a Highly Potent and Selective Type II Irreversible Bone Marrow Kinase in the X Chromosome [BMX] Kinase Inhibitor. J Med Chem. 2017 Mar 9;60[5] 1793-1816. |
More info
CHMFL-BMX-078 is a highly potent and selective type II irreversible inhibitor of BMX kinase, with an IC50 of 11 nM.