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Kinase Inhibitors

CD532 View larger

CD532

AT50110

CAS 1639009-81-6

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$28.00

$28.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $23.80 Total: $119.00
110 $20.16 Total: $201.60
125 $17.08 Total: $427.00
150 $14.56 Total: $728.00
1100 $12.60 Total: $1,260.00

Data sheet

Molecular FormulaC26H25F3N8O
Molecular Weight522.52
CAS Numbers1639009-81-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeN(C=1C=C(NN1)C2CCCC2)C3=NC(NC4=CC=C(NC(NC5=CC(C(F)(F)F)=CC=C5)=O)C=C4)=NC=C3
ReferencesGustafson WC, et, al. Drugging MYCN through an allosteric transition in Aurora kinase A. Cancer Cell. 2014 Sep 8;26[3] 414-427.

More info

CD532 is A highly potent Aurora A kinase inhibitor with an IC50 value of 45 nM. CD532 can block Aurora A kinase activity, drive MYCN degradation, and can directly interact with AURKA and induce global conformational transformation. CD532 can be used to study cancer.