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View larger BMS-986142
AT5138
CAS 1643368-58-4
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $103.70 | Total: $518.50 |
| 1 | 10 | $87.84 | Total: $878.40 |
| 1 | 25 | $74.42 | Total: $1,860.50 |
| 1 | 50 | $63.44 | Total: $3,172.00 |
| 1 | 100 | $54.90 | Total: $5,490.00 |
Data sheet
| Molecular Formula | C32H30F2N4O4 |
| Molecular Weight | 572.6 |
| CAS Numbers | 1643368-58-4 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1c(cccc1-n1c(=O)n(C)c2c(F)cccc2c1=O)-c1c(F)cc(C(N)=O)c2[nH]c3C[C@H](CCc3c12)C(C)(C)O |
| References | Watterson SH, et al. Discovery of 6-Fluoro-5-[R]-[3-[S]-[8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3[4H]-yl]-2-methylphenyl]-2-[S]-[2-hydroxypropan-2-yl]-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide [BMS-1986142] A Reversible Inhibitor of Bruton's Tyrosine Kinase [BTK] Conformationally Constrained by Two Locked Atropisomers. J Med Chem. 2016 Oct 13;59[19] 9173-9200. |
More info
BMS-986142 is a potent and highly selective reversible BTK inhibitor (IC50: 0.5 nM).