Kinase Inhibitors

NG25 View larger

NG25

AT5643

CAS 1315355-93-1

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$67.00

$67.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $30.15 Total: $3,015.00
150 $34.84 Total: $1,742.00
125 $40.87 Total: $1,021.75
110 $48.24 Total: $482.40
15 $56.95 Total: $284.75

Data sheet

Molecular FormulaC29H30F3N5O2
Molecular Weight537.58
CAS Numbers1315355-93-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ccnc5[nH]ccc45)c3)cc2C(F)(F)F)CC1
ReferencesWang Z , Zhang H , Shi M , et al. TAK1 inhibitor NG25 enhances doxorubicin-mediated apoptosis in breast cancer cells[J]. Scientific Reports, 2016, 6 32737.

More info

NG25 is a potent dual inhibitor of TAK1 and MAP4K2, with IC50s of 149 nM and 21.7 nM, respectively.