Kinase Inhibitors

CDK9-IN-15 View larger

CDK9-IN-15

AT60619

CAS 852678-17-2

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$35.00

$35.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $15.75 Total: $1,575.00
150 $18.20 Total: $910.00
125 $21.35 Total: $533.75
110 $25.20 Total: $252.00
15 $29.75 Total: $148.75

Data sheet

Molecular FormulaC16H11N3OS
Molecular Weight293.34
CAS Numbers852678-17-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOc1cccc2c(Nc3ncnc4sccc34)cccc12
ReferencesVan Duyne R, et al. Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription. J Mol Biol. 2013;425[4] 812-829.

More info

CDK9-IN-15 is a potent small molecule CDK9 inhibitor, which can block the phosphorylation of positive transcription elongation factor b (P-TEFb) on the C-terminal region of RNA Poly-II by degradation and inhibition of CDK9, inhibit transcription, and rapidly reduce the level of intracellular mRNA, thereby causing apoptosis of tumor cells.