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View larger (R)-STU104
AT60657
CAS 2767124-77-4
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $141.10 | Total: $705.50 |
| 1 | 10 | $119.52 | Total: $1,195.20 |
| 1 | 25 | $101.26 | Total: $2,531.50 |
| 1 | 50 | $86.32 | Total: $4,316.00 |
| 1 | 100 | $74.70 | Total: $7,470.00 |
Data sheet
| Molecular Formula | C18H18O4 |
| Molecular Weight | 298.33 |
| CAS Numbers | 2767124-77-4 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(C)C1=C2[C@H](CC(=O)C2=CC(OC)=C1)C3=CC=C(OC)C=C3 |
| References | Tang ML, et al. Discovery of First-in-Class TAK1-MKK3 Protein-Protein Interaction [PPI] Inhibitor [R]-STU104 for the Treatment of Ulcerative Colitis through Modulating TNF-? Production. J Med Chem. 2022 May 12;65[9] 6690-6709. |
More info
(R)-STU104 is a novel TAK1-MKK3 protein-protein interaction (PPI) inhibitor that inhibits TNF-? and suppresses the TAK1MKK3p38MnK1MK2elF4E signalling pathway by binding to MKK3 and disrupting TAK1 phosphorylation of MKK3. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.