Kinase Inhibitors

A-674563 2HCl(552325-73-2(fb-2hcl)) View larger

A-674563 2HCl(552325-73-2(fb-2hcl))

AT6139L

Molarity Calculation Cart®

HOW TO ORDER

$66.00

$66.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $29.70 Total: $2,970.00
150 $34.32 Total: $1,716.00
125 $40.26 Total: $1,006.50
110 $47.52 Total: $475.20
15 $56.10 Total: $280.50

Data sheet

Molecular FormulaC22H24Cl2N4O
Molecular Weight431.36
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.Cl.Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1
ReferencesLuo Y, Shoemaker A R, Liu X, et al. Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo.[J]. Molecular Cancer Therapeutics, 2005, 4[6] 977.

More info

A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.