Kinase Inhibitors

GNE-7915 View larger

GNE-7915

AOB87767

CAS No:1351761-44-8

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$15.00

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $6.75 Total: $675.00
150 $7.80 Total: $390.00
125 $9.15 Total: $228.75
110 $10.80 Total: $108.00
15 $12.75 Total: $63.75

Data sheet

Molecular FormulaC19H21F4N5O3
Molecular Weight443.4
CAS Numbers1351761-44-8
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity 99% (HPLC)

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A Blood-Brain Barrier (BBB) penetrable small molecule inhibitor of Leucine-Rich Repeat Kinase 2 (LRRK2)

References:

1. A.A. Estrada, et al., Discovery of Highly Potent, Selective, and Brain-Penetrable Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors, J. Med. Chem., 2012, 55 (22), pp 9416–9433
2. M.E. Kavanagh, et al, Bio.& Med. Chem Letters, 2013, 23 (13) Pages 3690–3696