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Kinase Inhibitors
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View larger IRAK4-IN-10
AT61931
CAS 2681278-09-9
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $457.30 | Total: $2,286.50 |
| 1 | 10 | $387.36 | Total: $3,873.60 |
| 1 | 25 | $328.18 | Total: $8,204.50 |
| 1 | 50 | $279.76 | Total: $13,988.00 |
| 1 | 100 | $242.10 | Total: $24,210.00 |
Data sheet
| Molecular Formula | C22H24N8 |
| Molecular Weight | 400.48 |
| CAS Numbers | 2681278-09-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N#CC=1C=CC=2C3=NC=C(C=4N=NN(C4)C5CCNCC5)C(NC(C)C)=C3NC2C1 |
| References | Sabnis RW. Novel Tricyclic Heteroaryl Compounds as IRAK4 Inhibitors for Treating Cancer, Autoimmune and Inflammatory Diseases. ACS Med Chem Lett. 2022 Feb 28;13[3] 336-337. |
More info
IRAK4-IN-10 (compound 75) is a potent IRAK4 inhibitor (IC50 = 1.5 nM) that can block the MyD88-dependent signaling pathway and has research potential in inflammatory diseases, autoimmune diseases, and cancer.