Kinase Inhibitors

AMPK activator 4 View larger

AMPK activator 4

AT62238

CAS 2493239-46-4

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$71.00

$71.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $31.95 Total: $3,195.00
150 $36.92 Total: $1,846.00
125 $43.31 Total: $1,082.75
110 $51.12 Total: $511.20
15 $60.35 Total: $301.75

Data sheet

Molecular FormulaC24H21ClN2O3
Molecular Weight420.89
CAS Numbers2493239-46-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)(Oc1ccc(Cl)cc1)C(=O)Nc1ccc(OCc2ccc(cc2)C#N)cc1
ReferencesSun G, et al. Discovery of AdipoRon analogues as novel AMPK activators without inhibiting mitochondrial complex I. Eur J Med Chem. 2020;200 112466.

More info

AMPK activator 4 is a potent and selective AMPK activator that does not inhibit mitochondrial complex I. It selectively activates AMPK in muscle tissue, dose-dependently improves glucose tolerance in normal mice, significantly reduces fasting glucose levels, and improves insulin resistance in dbdb diabetic mice. [AMPK activator 4 has hypoglycemic effects.]