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Kinase Inhibitors
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View larger JAK3-IN-14
AT67754
CAS 454234-24-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $163.20 | Total: $816.00 |
| 1 | 10 | $138.24 | Total: $1,382.40 |
| 1 | 25 | $117.12 | Total: $2,928.00 |
| 1 | 50 | $99.84 | Total: $4,992.00 |
| 1 | 100 | $86.40 | Total: $8,640.00 |
Data sheet
| Molecular Formula | C18H13N3O |
| Molecular Weight | 287.32 |
| CAS Numbers | 454234-24-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(=C1C=2C(NC1=O)=CC=C(C2)C=3C=CC=NC3)C4=CC=CN4 |
| References | Chen Y, et, al. Identification of an orally available compound with potent and broad FLT3 inhibition activity. Oncogene. 2016 Jun 9;35[23] 2971-8. |
More info
JAK3-IN-14 is a potent, selective and orally active FLT3 inhibitor, with IC50s of ?40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively.