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Kinase Inhibitors
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View larger FRAX486 HCL(1232030-35-1 free base)
AT6840L
CAS
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $13.95 | Total: $1,395.00 |
| 1 | 50 | $16.12 | Total: $806.00 |
| 1 | 25 | $18.91 | Total: $472.75 |
| 1 | 10 | $22.32 | Total: $223.20 |
| 1 | 5 | $26.35 | Total: $131.75 |
Data sheet
| Molecular Formula | C25H24Cl3FN6O |
| Molecular Weight | 549.86 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | FC1=CC(NC2=NC=C3C(N(C(C(C4=CC=C(C=C4Cl)Cl)=C3)=O)CC)=N2)=CC=C1N5CCNCC5.[H]Cl |
| References | Hayashi-Takagi A, et al. Proc Natl Acad Sci U S A. 2014, 111[17] 6461-6. |
More info
FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.