Kinase Inhibitors

AUTAC1 View larger

AUTAC1

AT74025

CAS 2241669-09-8

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$430.00

$430.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $193.50 Total: $19,350.00
150 $223.60 Total: $11,180.00
125 $262.30 Total: $6,557.50
110 $309.60 Total: $3,096.00
15 $365.50 Total: $1,827.50

Data sheet

Molecular FormulaC44H63FN8O11S
Molecular Weight931.08
CAS Numbers2241669-09-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC[C@@]1([C@@]2([C@@]3(CO3)CC[C@@H](OC(NCCCOCCOCCOCCCNC([C@H](CSC=4N(CC5=CC=C(F)C=C5)C6=C(N4)C(=O)N=C(N)N6)NC(C)=O)=O)=O)[C@H]2OC)[H])[C@H](CC=C(C)C)O1
ReferencesDaiki Takahashi, et al. AUTACs Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76[5] 797-810.e10.

More info

AUTAC1 is a MetAP2-targeted autophagy-mediated degrader (AUTAC) with potential anticancer activity that degrades MetAP2 and FKBP12 proteins and can be used to synthesize PROTAC.