Kinase Inhibitors

JSH-150 View larger

JSH-150

AT8484

CAS 2247481-21-4

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$26.00

$26.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.70 Total: $1,170.00
150 $13.52 Total: $676.00
125 $15.86 Total: $396.50
110 $18.72 Total: $187.20
15 $22.10 Total: $110.50

Data sheet

Molecular FormulaC24H33ClN6O2S
Molecular Weight505.08
CAS Numbers2247481-21-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOCCN[C@H]1CC[C@@H](CC1)Nc1cc(-c2csc(NCC3(CCOCC3)C#N)n2)c(Cl)cn1
ReferencesBeilei Wang, et al. Discovery of 4-[[[4-[5-chloro-2-[[[1s,4s]-4-[[2-methoxyethyl]amino]cyclohexyl]amino]pyridin-4-yl]thiazol-2-yl]amino]methyl]tetrahydro-2H-pyran-4-carbonitrile [JSH-150] as a novel highly selective and potent CDK9 kinase inhibitor. Eur J Med Chem. 13 September 2018.

More info

JSH-150 is a highly selective CDK9 inhibitor with an IC50 of 1 nM.