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Kinase Inhibitors

BOT-64 View larger

BOT-64

AT8705

CAS 113760-29-5

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$68.00

$68.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $57.80 Total: $289.00
110 $48.96 Total: $489.60
125 $41.48 Total: $1,037.00
150 $35.36 Total: $1,768.00
1100 $30.60 Total: $3,060.00

Data sheet

Molecular FormulaC15H15NO2S
Molecular Weight273.35
CAS Numbers113760-29-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC1(C)Cc2oc(=Nc3ccccc3)sc2C(=O)C1
ReferencesKim B H , Roh E , Lee H Y , et al. Benzoxathiole derivative blocks lipopolysaccharide-induced nuclear factor-kappaB activation and nuclear factor-kappaB-regulated gene transcription through inactivating inhibitory kappaB kinase beta.[J]. Molecular Pharmacology, 2008, 73[4] 1309-1318.

More info

BOT-64 is an IKK-2 inhibitor which targets the Ser177 andor Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathiole compound