Kinase Inhibitors

mTOR inhibitor 13 View larger

mTOR inhibitor 13

AT9310

CAS 1144075-44-4

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$280.00

$280.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $126.00 Total: $12,600.00
150 $145.60 Total: $7,280.00
125 $170.80 Total: $4,270.00
110 $201.60 Total: $2,016.00
15 $238.00 Total: $1,190.00

Data sheet

Molecular FormulaC24H22N6O2S
Molecular Weight458.54
CAS Numbers1144075-44-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeN(C(NC=1C=CC=NC1)=O)C2=CC=C(C3=NC(=C4C(=N3)C=CS4)N5CC6OC(C5)CC6)C=C2
ReferencesVerheijen JC, Yu K, Toral-Barza L, Hollander I, Zask A. Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3K. Bioorg Med Chem Lett. 2010 Jan 1;20[1] 375-9.

More info

mTOR inhibitor 13 is a selective mTOR inhibitor with IC50 of 0.29nM and 119nM for mTOR and PI3K?, respectively.