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Kinase Inhibitors

Compound 1T-0219 (SC) View larger

Compound 1T-0219 (SC)

AT9545

CAS 383147-92-0

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$126.00

$126.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $107.10 Total: $535.50
110 $90.72 Total: $907.20
125 $76.86 Total: $1,921.50
150 $65.52 Total: $3,276.00
1100 $56.70 Total: $5,670.00

Data sheet

Molecular FormulaC20H19N3O7
Molecular Weight413.38
CAS Numbers383147-92-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOC1=CC=C(C=C1)C(=O)ON=C1CCCCC1C1=C(C=C(C=C1)[N+]([O-])=O)[N+]([O-])=O
ReferencesMore SK, Vomhof-Dekrey EE, Basson MD. ZINC4085554 inhibits cancer cell adhesion by interfering with the interaction of Akt1 and FAK. Oncol Lett. 2019 Jun;17[6] 5251-5260. doi 10.3892ol.2019.10192. Epub 2019 Mar 27. PMID 31186741; PMCID PMC6507311.

More info

Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation.