Kinase Inhibitors

SB-747651A Dihydrochloride View larger

SB-747651A Dihydrochloride

AT9652

CAS 1781882-72-1

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$57.00

$57.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $25.65 Total: $2,565.00
150 $29.64 Total: $1,482.00
125 $34.77 Total: $869.25
110 $41.04 Total: $410.40
15 $48.45 Total: $242.25

Data sheet

Molecular FormulaC16H24Cl2N8O
Molecular Weight415.32
CAS Numbers1781882-72-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.Cl.CCn1c(nc2cncc(CNC3CCNCC3)c12)-c1nonc1N
ReferencesShaista Naqvi, et al. Characterization of the cellular action of the MSK inhibitor SB-747651A. Biochem J. 2012 Jan 1;441[1] 347-57.

More info

SB-747651A dihydrochloride is a chemical compound that serves as an ATP-competitive inhibitor for mitogen- and stress-activated kinase 1 (MSK1), featuring an IC50 of 11 nM. Additionally, this compound effectively inhibits PRK2, RSK1, p70S6K, and ROCK-II, showcasing its potential in inflammation research [1].