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Kinase Inhibitors
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View larger JAK3BTK-IN-1
AT9814
CAS 2674036-91-8
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $178.50 | Total: $892.50 |
| 1 | 10 | $151.20 | Total: $1,512.00 |
| 1 | 25 | $128.10 | Total: $3,202.50 |
| 1 | 50 | $109.20 | Total: $5,460.00 |
| 1 | 100 | $94.50 | Total: $9,450.00 |
Data sheet
| Molecular Formula | C25H28N8O |
| Molecular Weight | 456.54 |
| CAS Numbers | 2674036-91-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C1=C2C(=CNC2=NC(NC3=CN(CC)N=C3)=N1)C4=CC=CC=C4)[C@H]5CN(C(C=C)=O)CCC5 |
| References | Guobao Zhang, et al. Pyrimidopyrroles. Patent WO2021147952A1. |
More info
JAK3 BTk-in-1 is a dual JAK3BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important targets in autoimmune diseases. JAK3 BTk-in-1 simultaneously inhibited the BTKJAK3 signaling pathway, showing a synergistic effect. JAK3 BTK-in-1 is a potential compound for the treatment of immune-related diseases, such as autoimmune diseases, certain types of cancer (including lymphoma and leukemia), and other diseases that may be characterized by an unbalanced immune response.