Kinase Inhibitors

2-Cyanopyrimidine View larger

2-Cyanopyrimidine

AT7451

CAS 14080-23-0

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Data sheet

Molecular FormulaC5H3N3
Molecular Weight105.1
CAS Numbers14080-23-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeN#CC1=NC=CC=N1
ReferencesRankovic Z , Cai J , Kerr J , et al. Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K Improving selectivity over hERG[J]. Bioorganic and Medicinal Chemistry Letters, 2010, 20[21] 6237-6241.

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2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)