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> Pathway Inhibitors>Enzyme Inhibitors>Kinase Inhibitors>Oclacitinib (PF-03394197)

Kinase Inhibitors

Oclacitinib (PF-03394197) View larger

Oclacitinib (PF-03394197)

AOB87738

CAS No:1208319-26-9

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $12.75 Total: $63.75
110 $10.80 Total: $108.00
125 $9.15 Total: $228.75
150 $7.80 Total: $390.00
1100 $6.75 Total: $675.00

Data sheet

Molecular FormulaC15H23N5O2S
Molecular Weight337.15
CAS Numbers1208319-26-9
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Stock Solution Guide10 mMol/3.37 mg/1m L of DMSO
Purity98% by HPLC
SynonymPF03394197; PF-03394197; PF 03394197; Oclacitinib; Apoquel.
IUPAC/Chemical NameN-methyl-1-((1r,4r)-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide
InChl KeyHJWLJNBZVZDLAQ-HAQNSBGRSA-N
InChl Code InChI=1S/C15H23N5O2S/c1-16-23(21,22)9-11-3-5-12(6-4-11)20(2)15-13-7-8-17-14(13)18-10-19-15/h7-8,10-12,16H,3-6,9H2,1-2H3,(H,17,18,19)/t11-,12-
SMILES CodeO=S(C[C@H]1CC[C@H](N(C)C2=C3C(NC=C3)=NC=N2)CC1)(NC)=O
References1) Little PR, King VL, Davis KR, Cosgrove SB, Stegemann MR. A blinded, randomized clinical trial comparing the efficacy and safety of oclacitinib and ciclosporin for the control of atopic dermatitis in client-owned dogs. Vet Dermatol. 2014 Dec 12. doi: 10.1111/vde.12186. [Epub ahead of print] PubMed PMID: 25496303.

2) Gadeyne C, Little P, King VL, Edwards N, Davis K, Stegemann MR. Efficacy of oclacitinib (Apoquel(®) ) compared with prednisolone for the control of pruritus and clinical signs associated with allergic dermatitis in client-owned dogs in Australia. Vet Dermatol. 2014 Dec;25(6):512-e86. doi: 10.1111/vde.12166. Epub 2014 Aug 11. PubMed PMID: 25109820.

More info

 Also known as PF03394197, is a novel Janus kinase inhibitor