Leukotriene Receptors

SC-57461A View larger

SC-57461A

AOB31975

CAS No: 423169-68-0

 

Chemical Name: 3-[Methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic Acid Hydrochloride

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $6.75 Total: $675.00
150 $7.80 Total: $390.00
125 $9.15 Total: $228.75
110 $10.80 Total: $108.00
15 $12.75 Total: $63.75

Data sheet

Molecular FormulaC20H26ClNO3
Molecular Weight363.88
CAS Numbers423169-68-0
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical NameN-methyl-N-[3-[4-(phenylmethyl)phenoxy]propyl]-β-alanine hydrochloride
InChl KeySBBJJLDNKNNWFJ-UHFFFAOYSA-N
SMILES CodeCN(CCC(O)=O)CCCOC(C=C2)=CC=C2CC1=CC=CC=C1.Cl
References1) Penning et al (2002) Synthesis of potent leukotriene A4 hydrolase inhibitors. Identification of 3-[methyl[3-[4 (phenylmethyl)phenoxy]propyl]amino]propanoic acid. J.Med.Chem. 45 3482 PMID: 12139459

2) Askonas et al (2002) Pharmacological characterization of SC-57461A (3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid HCl), a potent and selective inhibitor of leukotriene A4 hydrolase I: in vitro studies. J.Pharmacol.Exp.Ther. 300 577 PMID: 11805219

3) Kachur et al (2002) Pharmacological characterization of SC-57461A (3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid HCl), a potent and selective inhibitor of leukotriene A4 hydrolase II: in vivo studies. J.Pharmacol.Exp.Ther. 300 583 PMID: 11805220
PubChem ID9820433

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Potent and Selective Inhibitor of Leukotriene A4 Hydrolase I