Leukotriene Receptors

AS-35 View larger

AS-35

AT14326

CAS 108427-72-1

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$249.00

$249.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $112.05 Total: $11,205.00
150 $129.48 Total: $6,474.00
125 $151.89 Total: $3,797.25
110 $179.28 Total: $1,792.80
15 $211.65 Total: $1,058.25

Data sheet

Molecular FormulaC21H20N6O4
Molecular Weight420.42
CAS Numbers108427-72-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C1C(=CN=C2C(=CC=CN12)COC3=CC=C(C(=O)C)C(O)=C3CCC)C4=NN=NN4
ReferencesKasai H, et al. Peptide leukotriene antagonistic activity of AS-35, a new antiallergic drug. Jpn J Pharmacol. 1992 Apr;58[4] 347-55.

More info

AS-35 is an orally effective, potent, and selective antagonist of leukotrienes, antagonizing LTC4-, LTD4-, and LTE4-induced ileum contractions with IC50 values of 8 nM, 4 nM, and 3 nM, respectively. It exhibits antiallergic activities.