Metabolites

DAMPA View larger

DAMPA

AOB5928

CAS: 19741-14-1

 

Chemical Name: Deoxyaminopteroic acid; NSC131463; 2,4-Diamino-N10-methylpteroic acid; 4-[(2,4-Diaminopteridin-6-yl)methyl-methylamino]benzoic acid

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QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $6.75 Total: $675.00
150 $7.80 Total: $390.00
125 $9.15 Total: $228.75
110 $10.80 Total: $108.00
15 $12.75 Total: $63.75

Data sheet

Molecular FormulaC15H15N7O2
Molecular Weight325.33
CAS Numbers19741-14-1
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymDAMPA; Deoxyaminopteroic acid; NSC131463; NSC-131463; NSC 131463;
IUPAC/Chemical Name4-[(2,4-Diaminopteridin-6-yl)methyl-methylamino]benzoic acid
InChl KeyLWCXZSDKANNOAR-UHFFFAOYSA-N
InChl CodeInChI=1S/C15H15N7O2/c1-22(10-4-2-8(3-5-10)14(23)24)7-9-6-18-13-11(19-9)12(16)20-15(17)21-13/h2-6H,7H2,1H3,(H,23,24)(H4,16,17,18,20,21)
SMILES CodeO=C(O)C1=CC=C(N(CC2=NC3=C(N)N=C(N)N=C3N=C2)C)C=C1
References1) Silva MF, Ribeiro C, Gonçalves VMF, Tiritan ME, Lima Á. Liquid chromatographic methods for the therapeutic drug monitoring of methotrexate as clinical decision support for personalized medicine: A brief review. Biomed Chromatogr. 2018 May;32(5):e4159. doi: 10.1002/bmc.4159. Epub 2018 Jan 12. Review. PubMed PMID: 29226354.

2) Subaihi A, Trivedi DK, Hollywood KA, Bluett J, Xu Y, Muhamadali H, Ellis DI, Goodacre R. Quantitative Online Liquid Chromatography-Surface-Enhanced Raman Scattering (LC-SERS) of Methotrexate and its Major Metabolites. Anal Chem. 2017 Jun 20;89(12):6702-6709. doi: 10.1021/acs.analchem.7b00916. Epub 2017 May 25. PubMed PMID: 28505414.

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Metabolite of methotrexate (MTX)