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View larger Aminoadipic acid
AT4705
CAS 542-32-5
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Data sheet
| Molecular Formula | C6H11NO4 |
| Molecular Weight | 161.16 |
| CAS Numbers | 542-32-5 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | |
| IUPAC/Chemical Name | |
| InChl Key | |
| InChl Code | |
| SMILES Code | C(C(C(O)=O)N)CCC(O)=O |
| References | Wang TJ, et al. 2-Aminoadipic acid is a biomarker for diabetes risk. J Clin Invest. 2013 Oct;123[10] 4309-17. |
More info
Aminoadipic acid (DL-2-Aminoadipic acid) (2-aminoadipate) is a metabolite in the principal biochemical pathway of lysine. It is an intermediate in the metabolism (i.e. breakdown or degradation) of lysine and saccharopine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor N-methyl-D-aspartate (NMDA). Aminoadipic acid has also been shown to inhibit the production of kynurenic acid, a broad spectrum excitatory amino acid receptor antagonist, in brain tissue slices.