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View larger (R)-5-Oxopyrrolidine-2-carboxylic acid
AT4814
CAS 4042-36-8
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Data sheet
| Molecular Formula | C5H7NO3 |
| Molecular Weight | 129.11 |
| CAS Numbers | 4042-36-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | OC(=O)[C@H]1CCC(=O)N1 |
| References | Palekar AG, et al. Accumulation of 50oxo-L-proline and 5-oxo-D-proline in the blood plasma in end stage renal disease. Biochem Med. 1975 Nov;14[3] 339-45. |
More info
(R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) is a cyclic derivative of glutamic acid, physiologically present in mammalian tissues. It releases GABA from the cerebral cortex and exhibits anti-anxiety effects in a simple approach-avoidance conflict situation in rats. In clinical pharmacology experiments, it significantly shortens the plasma half-life of ethanol during acute intoxication.