Metabolites

(R)-5-Oxopyrrolidine-2-carboxylic acid View larger

(R)-5-Oxopyrrolidine-2-carboxylic acid

AT4814

CAS 4042-36-8

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$54.00

$54.00 per 500 mg

Data sheet

Molecular FormulaC5H7NO3
Molecular Weight129.11
CAS Numbers4042-36-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC(=O)[C@H]1CCC(=O)N1
ReferencesPalekar AG, et al. Accumulation of 50oxo-L-proline and 5-oxo-D-proline in the blood plasma in end stage renal disease. Biochem Med. 1975 Nov;14[3] 339-45.

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(R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) is a cyclic derivative of glutamic acid, physiologically present in mammalian tissues. It releases GABA from the cerebral cortex and exhibits anti-anxiety effects in a simple approach-avoidance conflict situation in rats. In clinical pharmacology experiments, it significantly shortens the plasma half-life of ethanol during acute intoxication.