Metabolites

5-Methyluridine View larger

5-Methyluridine

AT5282

CAS 1463-10-1

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Data sheet

Molecular FormulaC10H14N2O6
Molecular Weight258.23
CAS Numbers1463-10-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(C)=C2
ReferencesMorris GS, et al. Use of biological fluids for the rapid diagnosis of potentially lethal inherited disorders of human purine and pyrimidine metabolism. Biomed Chromatogr. 1986 Jun;1[3] 109-18.

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5-Methyluridine (Thymine riboside) is an endogenous methylated nucleoside found in human fluids; methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls.DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents.