Metabolites

3-Methyladipic acid View larger

3-Methyladipic acid

AT5253

CAS 3058-01-3

More details

Molarity Calculation Cart®

HOW TO ORDER

$35.00

$35.00 per 500 mg

Data sheet

Molecular FormulaC7H12O4
Molecular Weight160.17
CAS Numbers3058-01-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(CCC(O)=O)CC(O)=O
ReferencesWierzbicki AS, et al. Refsum's disease a peroxisomal disorder affecting phytanic acid alpha-oxidation. J Neurochem. 2002 Mar;80[5] 727-35.

More info

3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-oxidation, and so the w-oxidation pathway is the only metabolic pathway available for phytanic acid degradation. This pathway produces 3-methyladipic acid as the final metabolite, which is excreted in the urine.