Metabolites

3-(Methylthio)propionic acid View larger

3-(Methylthio)propionic acid

AT5285

CAS 646-01-5

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Data sheet

Molecular FormulaC4H8O2S
Molecular Weight120.17
CAS Numbers646-01-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCSCCC(O)=O
ReferencesSurette R, et al. Formation of 3-methylthioacrylic acid from methionine by Streptomyces lincolnensis. Isolation of a peroxidase. J Antibiot [Tokyo]. 1976 Jun;29[6] 646-52.

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3-(Methylthio)propionic acid (4-Thiapentanoic acid) is one of the metabolites of methionine (especially of D-methionine). Cultures of Streptomyces lincolnensis accumulated 3-methylthioacrylic acid in amounts directly related to the concentration of methionine in the medium. The first intermediate in the pathway may be the keto acid, which is then oxidatively decarboxylated to 3-methylthiopropionic acid.