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> Metabolites>Guanosine 5'-triphosphate trisodium salt

Metabolites

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Guanosine 5'-triphosphate trisodium salt

AT4969

CAS 36051-31-7

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Data sheet

Molecular FormulaC10H13N5Na3O14P3
Molecular Weight589.13
CAS Numbers36051-31-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP([O-])([O-])=O)([O-])=O)(O)=O)N2C3=C(C(N=C(N3)N)=O)N=C2.[Na+].[Na+].[Na+]
ReferencesGutkind, Silvio J . Cell growth control by G protein-coupled receptors from signal transduction to signal integration[J]. Oncogene, 1998, 17[11] 1331-1342.

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Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates signal-transducing G proteins involved in cellular processes such as proliferation, differentiation, and activation of intracellular kinase cascades. It regulates proliferation and apoptosis through the hydrolysis by small GTPases Ras and Rho, and plays a role in vesicle docking, fusion, and formation via Rab. Additionally, GTP serves as an energy-rich precursor for the biosynthesis of DNA and RNA.