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Metabolites
- Protein Control Ligand
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View larger Guanosine 5'-triphosphate trisodium salt
AT4969
CAS 36051-31-7
Molarity Calculation Cart®
HOW TO ORDER
Data sheet
| Molecular Formula | C10H13N5Na3O14P3 |
| Molecular Weight | 589.13 |
| CAS Numbers | 36051-31-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP([O-])([O-])=O)([O-])=O)(O)=O)N2C3=C(C(N=C(N3)N)=O)N=C2.[Na+].[Na+].[Na+] |
| References | Gutkind, Silvio J . Cell growth control by G protein-coupled receptors from signal transduction to signal integration[J]. Oncogene, 1998, 17[11] 1331-1342. |
More info
Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates signal-transducing G proteins involved in cellular processes such as proliferation, differentiation, and activation of intracellular kinase cascades. It regulates proliferation and apoptosis through the hydrolysis by small GTPases Ras and Rho, and plays a role in vesicle docking, fusion, and formation via Rab. Additionally, GTP serves as an energy-rich precursor for the biosynthesis of DNA and RNA.