Metabolites

Trans-?2-?butene-?1,?4-?dicarboxylic acid View larger

Trans-?2-?butene-?1,?4-?dicarboxylic acid

AT5246

CAS 4436-74-2

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Data sheet

Molecular FormulaC6H8O4
Molecular Weight144.13
CAS Numbers4436-74-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC(=O)CCC=CC(O)=O
ReferencesJin SJ, et al. Identification of isomeric unsaturated medium-chain dicarboxylic acids in human urine. J Lipid Res. 1989 Oct;30[10] 1611-9.

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Trans-2-butene-1,4-dicarboxylic acid (3-Hexenedioic Acid) is a normal human unsaturated dicarboxylic acid metabolite with increased excretion in patients with Dicarboxylic aciduria caused by fatty acid metabolism disorders The urinary excretion of Trans-2-butene-1,4-dicarboxylic acid is increased in conditions of augmented mobilization of fatty acids or inhibited fatty acid oxidation.