Metabolites

Desmethyl Erlotinib hydrochloride View larger

Desmethyl Erlotinib hydrochloride

AT6619

CAS 183320-51-6

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$46.00

$46.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $20.70 Total: $2,070.00
150 $23.92 Total: $1,196.00
125 $28.06 Total: $701.50
110 $33.12 Total: $331.20
15 $39.10 Total: $195.50

Data sheet

Molecular FormulaC21H21N3O4
Molecular Weight415.87
CAS Numbers183320-51-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCO
ReferencesMeany HJ, et al. Cancer Chemother Pharmacol. 2008, 62[3], 387-392.

More info

Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for human EGFR and EGFR autophosphorylation in tumor cells.