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View larger 7-Hydroxymethotrexate
AT20339
CAS 5939-37-7
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $225.25 | Total: $1,126.25 |
| 1 | 10 | $190.80 | Total: $1,908.00 |
| 1 | 25 | $161.65 | Total: $4,041.25 |
| 1 | 50 | $137.80 | Total: $6,890.00 |
| 1 | 100 | $119.25 | Total: $11,925.00 |
Data sheet
| Molecular Formula | C20H22N8O6 |
| Molecular Weight | 470.44 |
| CAS Numbers | 5939-37-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NC1=C2C(NC(=O)C(CN(C)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=NC(N)=N1 |
| References | L Fahrig, et al. Pharmacokinetics of methotrexate [MTX] and 7-hydroxymethotrexate [7-OH-MTX] in rats and evidence for the metabolism of MTX to 7-OH-MTX. Cancer Chemother Pharmacol. 1989;23[3] 156-60. |
More info
7-Hydroxymethotrexate is the major metabolite of Methotrexate.Methotrexate is an inhibitor of folic acid, inhibiting dihydrofolate reductase, which prevents the conversion of folic acid to tetrahydrofolate, and inhibiting DNA synthesis.Methotrexate is also an inhibitor of metabolism.