Metabolites

Suberic acid View larger

Suberic acid

AT4734

CAS 505-48-6

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Data sheet

Molecular FormulaC8H14O4
Molecular Weight174.19
CAS Numbers505-48-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(CC(O)=O)CCCCC(O)=O
ReferencesGregersen N, et al. General [medium-chain] acyl-CoA dehydrogenase deficiency [non-ketotic dicarboxylic aciduria] quantitative urinary excretion pattern of 23 biologically significant organic acids in three cases. Clin Chim Acta. 1983 Aug 15;132[2] 181-91.

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Suberic acid (1,8-Octanedioic acid) is present in the urine of patients with fatty acid oxidation disorders. A metabolic breakdown product derived from oleic acid. Elevated levels of this unstaruated dicarboxylic acid are found in individuals with medium-chain acyl-CoA dehydrogenase deficiency (MCAD). Suberic acid is also associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency.