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View larger Adenine monohydrochloride hemihydrate
AT5081
CAS 6055-72-7
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Data sheet
| Molecular Formula | C5H8ClN5O |
| Molecular Weight | 189.6 |
| CAS Numbers | 6055-72-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O.Cl.Nc1ncnc2nc[nH]c12 |
| References | Gorzalka S, et al. Evidence for the functional expression and pharmacological characterization of adenine receptors in native cells and tissues. Mol Pharmacol. 2005 Mar;67[3] 955-64. |
More info
Adenine monohydrochloride hemihydrate is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor and also stimulates GTP?S binding (pEC50 values are 8.54 and 7.21 respectively).