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View larger 1,4-D-Gulonolactone
AT4719
CAS 6322-07-2
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Data sheet
| Molecular Formula | C6H10O6 |
| Molecular Weight | 178.14 |
| CAS Numbers | 6322-07-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | OC[C@@H](O)[C@@H]1OC(=O)[C@H](O)[C@@H]1O |
| References | Wolucka B A , Communi D . Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase[J]. Febs Journal, 2006, 273[19] 4435-4445. |
More info
1,4-D-Gulonolactone (D-Gulonic acid ?-lactone) (also known as reduced ascorbic acid, RAA) is the substrate of the enzyme L-gulono-1,4-lactone oxidoreductase (EC 1.1.3.8), which catalyzes the last step of the biosynthesis of L-ascorbic acid (vitamin C) in plants and animals. The enzyme L-Gulono-1,4-lactone oxidase is missing in scurvy-prone, vitamin C-deficient animals, such as humans. 1,4-D-Gulonolactone is present in human blood and has been used as one of the markers to compare changes in exercise-induced oxidative stress.