mTOR

WAY-600 View larger

WAY-600

AT6730

CAS 1062159-35-6

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$27.00

$27.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $12.15 Total: $1,215.00
150 $14.04 Total: $702.00
125 $16.47 Total: $411.75
110 $19.44 Total: $194.40
15 $22.95 Total: $114.75

Data sheet

Molecular FormulaC28H30N8O
Molecular Weight494.59
CAS Numbers1062159-35-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(N1CCC(CC1)n1ncc2c(nc(nc12)-c1ccc2[nH]ccc2c1)N1CCOCC1)c1cccnc1
ReferencesYu K, et al, Cancer Res, 2009, 69[15], 6232-6240.

More info

WAY-600 is a potent, ATP-competitive, and selective inhibitor of mTOR with an IC50 of 9 nM; it blocks mTORC1P-S6K(T389) and mTORC2P-AKT(S473) but not P-AKT(T308), and is selective for mTOR over PI3K? (>100-fold) and PI3K? (>500-fold).