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View larger Rheb inhibitor NR1
AT16741
CAS 2216763-38-9
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $60.35 | Total: $301.75 |
| 1 | 10 | $51.12 | Total: $511.20 |
| 1 | 25 | $43.31 | Total: $1,082.75 |
| 1 | 50 | $36.92 | Total: $1,846.00 |
| 1 | 100 | $31.95 | Total: $3,195.00 |
Data sheet
| Molecular Formula | C25H19BrCl2N2O3S |
| Molecular Weight | 578.3 |
| CAS Numbers | 2216763-38-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CN(C)C(=O)c1ccc(Cn2c(cc3c(Br)cc(Sc4ccc(Cl)c(Cl)c4)cc23)C(O)=O)cc1 |
| References | Mahoney SJ, et al. A small molecule inhibitor of Rheb selectively targets mTORC1 signaling. Nat Commun. 2018 Feb 7;9[1] 548. |
More info
Rheb inhibitor NR1 is a selective mTORC1 inhibitor that suppresses the phosphorylation of T389pS6K1 and enhances the phosphorylation of S473pAKT.