Muscarinic Receptor

DREADD agonist 21 View larger

DREADD agonist 21

AOB6927

CAS No: 56296-18-5

 

Chemical Name: 11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine

 

More details

Molarity Calculation Cart®

HOW TO ORDER

$17.00

$17.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $7.65 Total: $765.00
50 $8.84 Total: $442.00
25 $10.37 Total: $259.25
10 $12.24 Total: $122.40
5 $14.45 Total: $72.25

Data sheet

Molecular FormulaC17H18N4
Molecular Weight278.35
CAS Numbers56296-18-5
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymDREADD agonist 21; DREADD-agonist-21; DREADD agonist-21
IUPAC/Chemical Name11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine
InChl KeyJCBYXNSOLUVGTF-UHFFFAOYSA-N
InChl CodeInChI=1S/C17H18N4/c1-2-6-14-13(5-1)17(21-11-9-18-10-12-21)20-16-8-4-3-7-15(16)19-14/h1-8,18-19H,9-12H2
SMILES CodeC12=CC=CC=C1NC3=CC=CC=C3C(N4CCNCC4)=N2
References1) Giorgi A, etc. Brain-wide Mapping of Endogenous Serotonergic Transmission via Chemogenetic fMRI. Cell Rep. 2017 Oct 24;21(4):910-918.

2) Sun JJ, Ray RS. Tg(Th-Cre)FI172Gsat (Th-Cre) defines neurons that are required for full hypercapnic and hypoxic reflexes. Biol Open. 2017 Aug 15;6(8):1200-1208.

3) Sun HX, Wang DR, Ye CB, Hu ZZ, Wang CY, Huang ZL, Yang SR. Activation of the ventral tegmental area increased wakefulness in mice. Sleep Biol Rhythms. 2017;15(2):107-115.

More info

Potent muscarinic hM3Dq DREADD receptor agonist