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View larger Rolapitant hydrochloride
AT3724
CAS 858102-79-1
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $98.55 | Total: $9,855.00 |
| 1 | 50 | $113.88 | Total: $5,694.00 |
| 1 | 25 | $133.59 | Total: $3,339.75 |
| 1 | 10 | $157.68 | Total: $1,576.80 |
| 1 | 5 | $186.15 | Total: $930.75 |
Data sheet
| Molecular Formula | C25H27ClF6N2O2 |
| Molecular Weight | 536.94 |
| CAS Numbers | 858102-79-1 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.C[C@@H](OC[C@]1(CC[C@]2(CCC(=O)N2)CN1)c1ccccc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F |
| References | Rapoport B, Schwartzberg L, Chasen M, Powers D, Arora S, Navari R, Schnadig I. Eur J Cancer. 2016 Apr;57 23-30. |
More info
Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting, and orally active neurokinin 1 (NK1) receptor antagonist with a K_i of 0.66 nM, which does not interact with CYP3A4 and demonstrates potent centrally-mediated anti-emetic activity in both acute and delayed ferret emesis models [1] [2].