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NF-κB
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View larger (EZ)-IT-603
AT8799
CAS 292168-90-2
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $39.10 | Total: $195.50 |
| 1 | 10 | $33.12 | Total: $331.20 |
| 1 | 25 | $28.06 | Total: $701.50 |
| 1 | 50 | $23.92 | Total: $1,196.00 |
| 1 | 100 | $20.70 | Total: $2,070.00 |
Data sheet
| Molecular Formula | C11H9BrN2O3S |
| Molecular Weight | 329.17 |
| CAS Numbers | 292168-90-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cc(Br)cc(C=C2NC(=S)NC2=O)c1O |
| References | Shono Y , Tuckett A Z , Ouk S , et al. A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity[J]. Cancer Discovery, 2014, 4[5] 578-91. |
More info
(EZ)-IT-603 is a cell-permeable c-Rel inhibitor (IC50: 3?M) that directly and reversibly binds to c-Rel, altering its conformation and inhibiting its DNA binding and transcriptional activity.